Daily News Mug

October 31, 2014
by The Mug
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Auspex Pharmaceuticals: Putting an End to Orphan Diseases

Orphan diseases is a collective term used for those rare diseases that affect a minority. In the United States, there are about 200,000 people who are affected with these medical conditions. Headquartered in San Diego, California, Auspex Pharmaceuticals is one of the businesses that have taken on the challenge of developing and commercializing novel medications for these rare conditions.

These diseases include Tourette syndrome, tardive dyskinesia, hyperkinetic movement disorders and the Huntington’s disease. The company has product candidates to address these unmet areas of medicine. Their lead compound is named the SD-809 which is primarily developed to come up with treatment for these involuntary movements that are characterized by various neurological disorders. This product is currently in Phase 3 of clinical trial and was drawn from the Tetrabenazine, the only FDA approved drug for Huntington’s disease.

Auspex Pharmaceutical is drawing the potential of SD-809 as a basal medication for other neurological disorders. Through their expertise in deuterium chemistry, they are finding means to change the quality of life of these few patients.

October 28, 2014
by The Mug
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Berry Plastics: One of the World’s Largest Plastic Producers

There is a lot of usage of plastics. Every day, we encounter plastics in any form. These plastics could be used for storage, for packaging, for marketing purposes and for just about any purpose it may serve. As plastics threaten the world’s cleanliness and the survivability of its flora and fauna diversity, plastic manufacturers also find the means to control the alarming rate of damage it has on the environment.

Berry Plastics is one of those businesses that continuously innovate their product offerings, not just to cater to the needs of their business partners, but also to address environmental issues and its impact to the community. The company has been around since 1967 and is considered to be one of the world’s largest manufacturers of plastic packaging materials. The business started out as Imperial Plastics and through several acquisitions and mergers, became Berry Plastics, a multi-billion global venture.

The business is considered as one of the most aggressive plastic businesses out there. Since 1988, the company has acquired 30 plastic businesses across the globe. It is one of the companies that are actively in the lookout for possible takeovers. As a global business, they have 80 manufacturing plants around the world. Their annual sales are reported to be more than $5 billion. It was in March 2012 that the company has gone public. Today, the business remains publicly held on the New York Stock Exchange and trades its common stocks under the symbol BERY.

The operations of the company are divided into the different plastic types they manufacture: Engineered Materials, Rigid Open Top, Rigid Closed Top and Flexible Packaging. Among its largest clients are Coca-Cola, Pepsi-Cola, Avon, Unilever, McDonalds, Colgate-Palmolive,Kraft Foods, L’Oreal, Procter & Gamble and Starbucks, among others. Berry Plastics remain to be one of the largest suppliers of plastics to the personal care, food, retail, building supplies, dairy, promotional and industrial companies around the world.

October 24, 2014
by The Mug
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AmTrust Bank: A Subsidiary of the New York Community Bank

Considered probably as one of the most resilient financial institutions in the country, AmTrust Bank traces its history in 1889 as the Ohio Savings Bank. The company is one of the many financial institutions that have been impacted by the recession the country is experiencing.

Despite being closed down in 2009, the business got revived the following year. During the melt down of the business, all of its deposit accounts were moved to the New York Community Bank. As the latter expanded its operations in Cleveland, the business got revived. Together with its rebirth, the company’s original brand name also got revived as another subsidiary of NYCB. It now functions as a division of the New York Community Bank. The company offers construction lending, investment and insurance, mortgage, commercial and retail banking.

Starting out as a savings and loan association AmTrust Bank was once considered as one of the 20 largest mortgage lenders in the country. Together with 6 other brand names, they form the NYCB Family of Banks.

October 21, 2014
by The Mug
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Amgen: The World’s Largest Biotechnology Firm

Considered as the world’s largest biotechnology firm, Amgen is an American biopharmaceutical company headquartered in Thousand Oaks, California. The business was formerly known as Applied Molecular Genetics. The current business name is a portmanteau of the former name of the enterprise which started out in 1980. It was  three years after that the business adopted its current brand name.

The growth of the business is mainly attributed to its organic expansion and strategic acquisition. Since the time of its inception, the company has made five major corporate acquisitions. From 1994 until 2013, the business was able to acquire 15 biopharmaceutical businesses that are in line with the company’s mission of becoming the biggest firm in the world.  As of, there are several products that the company manufactures and markets. They have about 12 approved drugs that are used to treat 17 medical conditions and several other therapeutics that are on its clinical testing pipeline.

Amgen is best known for their drugs used to prevent infections of those patients who are undergoing chemotherapy. These two drugs are somehow interrelated and are marketed under the brand names Neulasta and Neupogen. They also have a medication that has been approved for rheumatoid arthritis and other autoimmune diseases. This tumor necrosis factor blocker is marketed under the name Enbrel. Amgen is also the producer and marketer of drugs like XGEVAm Aranesp, Epogen, Prolia, Sensipar/Mimpara, Vectibix and Nplate. They also have three other products that were developed by their team of experts and were later sold off and licensed to other businesses: Kineret, SteamGen and Kepivance.

The novel therapeutics that Amgen creates are marketed around the world. These products and all the services offered by the company help generate their annual income of more than $15.58 billion. The company is listed as a major component of the S&P 500, the NASDAQ 100 and the Russell 3000 Indices. It continues to be publicly held on the NASDAQ under the symbol AMGN.

October 17, 2014
by The Mug
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Workday, Inc.: Managing Businesses with Mobility

Following the hostile takeover of PeopleSoft, its founder David Duffield and Aneel Bhusri created another venture, this time focusing on a cloud-based platform. The partners set off to create Workday, Inc. in 2005. Their business is registered as a vendor of software for human capital management and financial management.

Through the expertise and connections of these two gentlemen, they were able to put up a business that has attracted more than 100 companies in 46 countries in less than 3 years of its inception. Through the services they provide, businesses are given assistance in managing their resources, financial accounting and revenue while maximizing the efficiency of their people. Because of the company’s cloud-based platform, they are able to provide busy executives and senior leadership the mobility they need to still work while on the go.

The products offered by Workday, Inc. remains to be competitive in the market. Not only are they offering their systems at a reasonable cost, they also offer their products with major updates provided every 6 months.

October 14, 2014
by The Mug
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TD Ameritrade: Offering Financial Freedom Since 1975

From a small investment banking firm, TD Ameritrade has grown to become the 746th largest U.S. firm in 2008. The company today is an online broker that has more than 5,836,000 accounts. The business is owned by TD Ameritrade Holding Corporation and is based in Omaha, Nebraska.

The company is publicly traded on the New York Stock Exchange and has about $481 billion in total client assets. As a brokerage firm, the company offers futures, ETFs, mutual funds, margin lending, preferred and common stocks, fixed income, cash management services and option trades. The company started out as the First Omaha Securities, Inc. and later on evolved to become the Ameritrade Clearing, Inc. and eventually to becoming TD Ameritrade. The business is one of the minority firms that were able to make a breakthrough after the Securities and Exchange Commission abolished the use of fixed brokerage commissions. Since its inception 35 years ago, the company continues to provide individual investors more access to the Wall Street.

TD Ameritrade continues to empower their clients to pursue their dreams of financial freedom and has provided them easy access to all the resources, education and services that would make them break through. Other than being a trusted partner in seeking financial independence, the company has also made a lot of firsts in the industry. Among its firsts is the touch-tone phone trading which it offered in 1988. It was also the first business to provide online trading in 1994 after it acquired K. Aufhauser & Co. Ameritrade was also the first company to go paperless and introduced the first online account opening process. As the business continued to advance the future of trading, it also strengthened its position in the market.

As more and more investors come to trust the service provided by Ameritrade, more trading transactions are done online. To date, there are roughly more than 400,000 trades placed by their clients every day.

October 10, 2014
by The Mug
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Sirona Dental Systems: World’s Largest Dental Equipment Manufacturer

Functioning as a subsidiary of Siemens, Sirona Dental Systems became an independent business in 1997. The company today is known as the world’s largest supplier of dental equipment. Headquartered in Long Island, New York, the company has global reach with products sold in more than 100 countries.

The products manufactured by Sirona are used for dental diagnosis and for restoration. They are best known for developing and marketing the world’s first dental X-ray unit, the REKOR in 1905. The product portfolio of the company includes dental treatment instruments, imaging systems, dental diagnostic products and materials and equipment for restoration. Their operations are divided into four segments: Instruments, Imaging Systems, Dental CAD/CAM Systems and Treatment Centers.

There are more than 450 distribution facilities around the world that Sirona operates and owns. It is through this network of distribution centers that they are able to market their products to dental practitioners, laboratories and clinics.

October 7, 2014
by The Mug
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ResMed: Giving the World a Good Night’s Sleep

Sleep is essential for every living thing to continue its existence. It is the body’s means of recuperating and resting from a day’s activity. It is the easiest and simplest means of rejuvenating our tired bodies. There are, however, some factors that might hamper our getting of restful sleep. ResMed is an expert in this arena and no other company has a better understanding of sleep disorders than they do.

Founded in 1989, the company has been providing the world the technology to diagnose and effectively address any sleep disorder especially obstructive sleep apnea (OSA). In a study conducted in 2012, results have shown that inadequate supply of oxygen to the body during sleep because of apnea is linked to increase vascular and tumor growth. These instances would eventually lead to higher instances of worsening into cancer. In the United States alone, it was surveyed that 24% of all middle-aged Americans are suffering from at least moderate sleep apnea. These individuals carry on with their lives without having their sleep disorders diagnosed or untreated.

Statistically, the ballooning number of individuals who are having sleep apnea disorders is causing $3.4 billion annually in medical costs. It is in this picture that ResMed comes in. The company provides not just the United States, but the entire world, the most recent technology to use in the diagnosis, treatment and management of sleeping disorders, particularly sleep-disordered breathing. The business is now a global leader in sleep medicine and non-invasive ventilation during sleep. Their products and services are marketed in over 70 countries through their network of distributors.

With the innovative products that ResMed introduces to the market, every individual is now guaranteed a good night’s sleep. Not only is the business addressing an impending issue in the healthcare industry, but it’s also promoting a healthier lifestyle by giving everyone the rejuvenating sleep we need.

October 3, 2014
by The Mug
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Pandora Media: Your Music Resource

Pandora Media is one of the companies in the United States that have a strong presence in the business of providing customized radio stations. The company got engaged in the licensing of transitional strategy of technology to businesses like Tower Records, Barnes & Noble, Best Buy and AOL. This venture, however, nearly failed that the company reverted to its original business model.

The business is the owner of Pandora Internet Radio. Also known as Pandora Radio or simply Pandora, this offering provides music recommendation service and music streaming. This product is only made available in the United States, New Zealand and in Australia and serves as the custodian of the Music Genome Project. In 2013, the company announced that it has already reached more than 200 million users, of which 70 million are active every month.

Other than their web-based music streaming site, they also offer an application for mobile listening which they recently modified to remove the cap of 40 hours per month bandwidth.

September 30, 2014
by The Mug
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Mylan: The World’s Second Largest Generic and Specialty Pharmaceutical Company

It is in Cecil Township, Pennsylvania that Mylan holds its headquarters. The company is a billion dollar business that generates more than $6.80 billion in annualized revenue and is engaged in the distribution of specialized and generic drugs. As a global business, the company has presence in the North America, Asia Pacific, Europe, the Middle East and in Africa.

From its inception in 1961, the company has grown to become the second largest generic and specialty pharmaceuticals in the world. It has presence in more than 150 countries and has more 1,000 products being marketed. They have over 22,000 employees around the world that helps in the manufacturing of these drugs and the distribution of their finished products. Their global manufacturing output is estimated to be more than 45 billion doses.

The business continues to provide the world with affordable and more accessible medicine to improve wellbeing. For more than 50 years, they remain anchored to their commitment to help patients get better. Their first produced and marketed product was the Penicillin G. When they got the approval of the FDA to start selling their offering, they started broadening their product portfolio. Some of the first few products they offered include analgesics, generic antibiotics, diuretics, antihistamines and tranquilizers. These products were marketed to drug store chains, large drug companies and mail-order drug providers.

The growth of the company is attributed to its organic growth and strategic acquisition. Through the years, the company has made several substantial acquisitions that have helped shape the Mylan that it is today. When the business purchased the India-based Matrix Laboratories Limited and the Germany-based Merck KGaA, the business became the second largest generic pharmaceutical company.

Mylan was founded by Milan Puskar and Don Panoz in White Sulphur Springs, West Virginia. The company started out as Milan Pharmaceuticals and naming rights of the enterprise was made by tossing a coin of its founders.